Key events in the spread of Ebola

Sanitized gloves and boots hang to dry as a burial team collects Ebola victims for cremation in Monrovia, Liberia, on Oct. 2. (John Moore / Getty Images)

It began in December 2013 in a village deep in the forests of southeastern Guinea, when a 2-year-old boy named Emile developed a mysterious illness.

But it wasn’t until August that the World Health Organization conceded that the worst Ebola outbreak on record had become an international public health emergency. By then, the deadly tide had reached Nigeria, Africa’s most populous nation. Infections soon cropped up in the U.S. and Western Europe.

Here are some key events in the disease’s spread. Click the check boxes below to add and remove events from specific regions.

Tags:
  Europe
  Guinea
  International
  Liberia
  Nigeria
  Senegal
  Sierra Leone
  United States
Sources: WHO, CDC, MapBox, OpenStreetMap
Sources: WHO, CDC, MapBox, OpenStreetMap (Los Angeles Times graphics)

Emile, a 2-year-old boy in Guinean village of Meliandou, dies of a mysterious sickness, becoming West Africa’s first Ebola victim.

Tagged as
Guinea

Amid a multitude of deadly diseases, Ebola spreads without being noticed.

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International

The World Health Organization publishes notification of a “rapidly evolving” Ebola outbreak in Guinea involving 49 patients and 29 deaths. Suspected cases in Sierra Leone and Liberia are being investigated.

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Guinea

The WHO reports that two Liberians tested positive for the Ebola virus after traveling to Guinea, including a 35-year-old woman who died March 21.

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Liberia
(Los Angeles Times graphics)

Dozens of mourners attend the funeral of a traditional healer who contracted Ebola while treating patients. The funeral, in Koindu, Sierra Leone, helps the virus spread and may be linked to 365 Ebola deaths, local health authorities say.

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Sierra Leone

Sierra Leone health authorities confirm their first Ebola case, a young woman admitted to a government hospital in Kenema after a miscarriage.

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Sierra Leone

An international research team sequences the genome of the Zaire strain of the Ebola virus. Researchers around the world begin studying it for clues about how to treat patients or develop drugs.

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International

Global toll to date: 528 cases, 337 deaths

Doctors Without Borders says the epidemic is “out of control.” The group says it has reached the limit of what it can do to fight the outbreak.

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International

The U.S. Centers for Disease Control and Prevention reports that the outbreak appeared to be running out of steam in Liberia and Guinea in late April, only to resurge in late May and spread to Sierra Leone.

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International

Liberian American Patrick Sawyer ignores the advice of medical officials and flies from Monrovia to Lagos, spreading Ebola to Nigeria. He dies five days later, and the virus goes on to sicken 19 and kill eight, the WHO says.

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Nigeria

Reviving a practice common during the medieval Black Death, the leaders of Guinea, Liberia and Sierra Leone announce plans to set up a cordon sanitaire. Troops are deployed to seal off the area where the three countries meet, a region that accounts for about 70% of the Ebola cases so far.

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International

Global toll to date: 1,323 cases, 729 deaths

Dr. Kent Brantly, a 33-year-old American who contracted Ebola while working in Liberia, is taken to Emory University Hospital in Atlanta. He becomes the first patient with Ebola to be treated on U.S. soil.

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United States

Nancy Writebol, a 59-year-old American missionary who contracted the virus while working in Liberia, arrives at Emory University Hospital. Both Writebol and Brantly make full recoveries after being treated with the experimental drug ZMapp, though it is unclear whether the drug was helpful.

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United States

Global toll to date: 1,779 cases, 961 deaths

The WHO Emergency Committee declares a Public Health Emergency of International Concern, saying the Ebola outbreak in West Africa constitutes a public health risk to other states and requires a coordinated international response.

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International

A WHO panel sanctions the use of experimental drugs to fight the epidemic, though supplies are extremely limited.

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International

A 21-year-old man who was being monitored by health authorities in Guinea flees to Dakar in neighboring Senegal, becoming that country’s first and only Ebola case. He is released from a hospital Sept. 19.

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Senegal

Clashes erupt as security forces seal off a Monrovia slum after residents attacked an Ebola screening center. The residents chased away sick patients and removed bloody sheets.

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Liberia

Global toll to date: 2,615 cases, 1,427 deaths

The WHO acknowledges that its Ebola counts underestimate the true number of cases. It cites the existence of “shadow zones,” or small villages where outbreak rumors can’t be investigated because of public resistance or lack of staff.

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International

The WHO warns that the Ebola outbreak is accelerating and could infect more than 20,000 people before it is brought under control.

The National Institute of Allergy and Infectious Diseases says it will begin human tests of a vaccine developed by the U.S. military and GlaxoSmithKline.

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International

The National Institutes of Health unveils plan to speed development and regulatory approval of ZMapp.

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International

The WHO endorses the use of blood transfusions from recovered patients to boost antibodies for the sick.

American aid worker Dr. Rick Sacra is taken to the University of Nebraska Medical Center after contracting Ebola in Liberia. He will make a full recovery after receiving experimental treatments, including blood plasma transfusions from Brantly and the drug TKM-Ebola.

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United States

Another patient with Ebola is admitted to Emory University Hospital. No details are released, but on Oct. 15 the patient says in a statement that he or she is recovering and anticipates being released soon.

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United States
A 2011 photograph shows Thomas Eric Duncan, who died of Ebola in Dallas on Oct. 8, at a wedding in Ghana.
A 2011 photograph shows Thomas Eric Duncan, who died of Ebola in Dallas on Oct. 8, at a wedding in Ghana. (Wilmot Chayee / Associated Press)

In Liberia, Thomas Eric Duncan, 42, joins neighbors on a frantic search to find a hospital or clinic that will admit a pregnant and desperately ill 19-year-old woman.

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United States

A team dispatched by the Guinean government to educate people about Ebola is attacked with clubs and stones in the village of Womme. Eight officials and journalists are killed.

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Guinea

President Obama says he is sending up to 3,000 military personnel to West Africa, where they will set up 17 treatment centers and train healthcare providers.

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United States

The U.N. Security Council declares the Ebola crisis in West Africa a threat to international peace and security.

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International
Sources: WHO, CDC, MapBox, OpenStreetMap
Sources: WHO, CDC, MapBox, OpenStreetMap (Los Angeles Times graphics)

Duncan boards a plane in Monrovia, Liberia, to visit family in Dallas.

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United States

Sierra Leone begins a nationwide lockdown to identify and count cases of Ebola. The country’s residents are required to stay home for three days while healthcare workers and volunteers go door to door searching for Ebola victims and distributing information about the virus.

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Sierra Leone

U.N. Secretary-General Ban Ki-moon calls for a “twentyfold surge in care, tracking, transport and equipment” to curb the epidemic, which is doubling in size about every three weeks.

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International

Duncan seeks care at Texas Health Presbyterian Hospital in Dallas for a fever, sharp headache and other symptoms. He is sent home with antibiotics.

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United States

Duncan returns to the hospital in an ambulance and is placed in isolation. He will receive brincidofovir, an experimental broad-spectrum antiviral drug.

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United States

Global toll to date: 6,574 cases, 3,091 deaths

Tests performed by the CDC and a Texas laboratory confirm that Duncan has Ebola, the first case diagnosed on U.S. soil.

The WHO announces that Ebola outbreaks in Senegal and Nigeria are under control.

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United States

NBC says a freelance cameraman in Liberia has contracted the virus and will be flown back to the U.S. for treatment. The journalist, U.S. native Ashoka Mukpo, will be taken to the Nebraska medical center Oct. 6. He will receive a blood transfusion from Brantly and be treated with brincidofovir, the same drug Duncan got.

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United States

Teresa Romero Ramos tests positive for Ebola in Spain, becoming the first person known to have contracted the virus outside West Africa in the current outbreak. The nursing assistant had treated two infected missionaries.

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Europe

Duncan dies at Texas Health Presbyterian Hospital.

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United States

Dr. Nancy Snyderman and other members of the NBC News crew that worked with Mukpo in West Africa go out in New Jersey, violating their quarantine.

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United States

Global toll to date: 8,399 cases, 4,033 deaths

Nina Pham, a 26-year-old nurse who had treated Duncan at Texas Health Presbyterian Hospital, reports having a fever and is put into isolation at the Dallas hospital.

Amber Vinson, a 29-year-old nurse who also had treated Duncan at the hospital, flies to Ohio with approval from the CDC.

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International
(Los Angeles Times graphics)

Tests performed by the CDC confirm Pham has Ebola. She stays in isolation at the Dallas hospital.

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United States

Vinson flies from Ohio back to Texas with CDC approval despite having a slight fever.

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United States

Vinson enters isolation at Texas Health Presbyterian Hospital.

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United States

Vinson is diagnosed with Ebola and transferred to Emory University Hospital in Atlanta.

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United States
Nina Pham in an undated photograph.
Nina Pham in an undated photograph. (Courtesy of Jennifer Joseph)

Pham is transferred to a National Institutes of Health clinic in Bethesda, Md.

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United States

The WHO declares Senegal to be free of Ebola.

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Senegal
Ron Klain is a longtime confidant to Democratic presidents and presidential candidates. Former colleagues said he brings an in-depth knowledge of federal agencies and processes to the job of "Ebola czar."
Ron Klain is a longtime confidant to Democratic presidents and presidential candidates. Former colleagues said he brings an in-depth knowledge of federal agencies and processes to the job of "Ebola czar." (Revolution LLC)

The Obama administration appoints an “Ebola czar,” advisor Ron Klain.

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United States

Teresa Romero Ramos in Spain no longer has any traces of Ebola in her blood, a test shows.

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Europe

The WHO declares Nigeria to be free of Ebola.

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Nigeria

American journalist Ashoka Mukpo and nurse Amber Vinson no longer have any traces of Ebola in their blood, tests show.

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United States
(Los Angeles Times / Bing Maps)

Dr. Craig Allen Spencer enters isolation at Bellevue Hospital in New York City and is diagnosed with Ebola. He had recently worked with Doctors Without Borders in Guinea.

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United States

Global toll to date: 10,141 cases; 4,922 deaths

Mali records its first Ebola case: a 2-year-old girl taken to the country by a relative after her mother died of Ebola in Guinea.

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International

Nina Pham, declared free of Ebola, is released from the NIH clinic and meets President Obama.

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United States
Kaci Hickox
Kaci Hickox (University of Texas at Arlington / Associated Press)

Nurse Kaci Hickox — who, despite testing negative for Ebola, has been quarantined for three days in a tent on the grounds of Newark University Hospital in New Jersey after returning from Sierra Leone — will be released. The decision to quarantine her caused an outcry.

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United States

Amber Vinson, the second of two Dallas nurses diagnosed with Ebola, is free of the disease and is discharged from Emory University Hospital in Atlanta.

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United States